On wiki.wikimedia.it, I recently observe a very severe performance degradation on all pages which embed images from Wikimedia Commons: typically, time to first byte is over 9 seconds, while it's less than 1 on any page which doesn't include remote images. http://www.webpagetest.org/result/150929_GX_HFJ/1/details/
The local configuration for InstantCommons/remote files can probably be improved, but however bad a local configuration is this should not happen. Can't MediaWiki just serve the HTML whatever the status of the thumbnails is?