during disk-intensive operations (e.g. swift rebalance or mysql alter table) we've seen the check_hpssacli nrpe check timing out on newer hp machines. The timeout has been increased to 40s already but sometimes that doesn't seem sufficient.
Swift machines are a bit peculiar in which they have all disks in raid0, so for each disk there's a physical volume and a logical volume to be checked.
MySQL is not peculiar and that also happens when there is high io_activity.