This may be related to T147827: Cursoring across focusable nodes has problems in Safari 10.
- Start in the visual editor/visual mode.
- Add wikitext that looks like this: Sentence.<ref>One</ref><ref>Two</ref> Next sentence.
- Click in the middle of the sentence.
- Try to use arrow keys to select one of those refs.
Result: It skipped from "Sentence." to "Next" without selecting either ref.