Python 2 is end-of-life; we should be using Python 3 instead.
Most services with CI are already being tested using Python 3. The bulk of our projects simply need /usr/bin/python3 as the interpreter and Python 3 versions of libraries installed (python3-xxx instead of python-xxx).
This is already in progress as a KR for this quarter; opening a task for it as well to make it easier to group together the related patches.