A year ago I tried to use First Contentful Paint to sync the speed our synthetic tests but its easier and makes more sense to use time to first byte now when it's available in the Chrome User Experience report. That way our synthetic tests try to match our 75 percentile (of Chrome users).
On mobile English Wikipedia TTFB is 638 ms and desktop 467 ms (https://grafana.wikimedia.org/d/t_bhsNGMk/chrome-user-experience-report?orgId=1).
In our testing today the TTFB for emulated mobile 450 ms is and desktop 190 ms for first view (warm cache is faster).