There are many things (like the titles of movies, example: Q836821) that have two language variations, one for Spain ("Guía del autoestopista galáctico") and one for Hispanic America ("Guía del viajero intergaláctico"). The policy on Spanish Wikipedia when this happens, is to use the English title, however, this means that the item's label in Wikidata is also in English and is not resolvable.
To resolve this, I propose that an es-ES language be added to Wikidata (and I suppose StructuredDataOnCommons). This way the Spanish label can be added in both variations, just like it can be in en, en-GB, en-CA etc.