After replacing nginx with ats-tls on cp5001 and running smoothly for 1 hour the following icinga alert was triggered:
PROBLEM - HTTPS Unified ECDSA on cp5001 is CRITICAL: SSL CRITICAL - failed to connect or SSL handshake:Connection reset by peer
Further inspection on cp5001 showed TLS handshake errors using openssl s_client -connect 127.0.0.1:443 -status
After depooling the host I failed to reproduce the issue with synthetic requests using curl
traffic_server showed the following metrics regarding SSL erros:
proxy.process.ssl.ssl_error_want_write 1249276 proxy.process.ssl.ssl_error_want_read 8512210 proxy.process.ssl.ssl_error_want_x509_lookup 0 proxy.process.ssl.ssl_error_syscall 483415 proxy.process.ssl.ssl_error_read_eos 0 proxy.process.ssl.ssl_error_zero_return 57254 proxy.process.ssl.ssl_error_ssl 12721