Please see report at mediawiki.org. It seems that @Oscar is having problems with this extension. Disabling scripts and gadgets didn't helped resolve the issue. If you could look into this it'd be appreciated.
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It was the webshield on Avast Antivirus.
Basically, is some kind of error with Avast, I just turned the webshield on/off. Restart the system, and now Apertium (and the auto-save) seems to be working.