Having long-lived temp folders isn't a reasonable expectation anymore:
Oct 17 07:04:44 thumbor1001 thumbor@8837[74679]: 2016-10-17 07:04:44,645 8837 thumbor:ERROR [BaseHandler] get_image failed for url `http%3A//ms-fe.svc.eqiad.wmnet/v1/AUTH_mw/wikipedia-commons-local-public.89/8/89/Flag_of_Antigua_and_Barbuda.svg`. error: `[Errno 2] No such file or directory: '/srv/thumbor/tmp/thumbor@8837/tmp_nWyEZ/source_file'` Oct 17 07:03:02 thumbor1001 thumbor@8825[71257]: CommandError: (['/usr/bin/vips', 'shrink', '/srv/thumbor/tmp/thumbor@8825/tmpv2KVW9', '/srv/thumbor/tmp/thumbor@8825/tmp7Cl9Rr/vips_result.png', '31', '31'], '', 'vips__file_open_write: unable to open file "/srv/thumbor/tmp/thumbor@8825/tmp7Cl9Rr/vips_result.png" for writing\n', 1)
The solution is simply to stop creating a temp folder and named temp files and just used regular temp files.