By their structure, permalinks can be long: #c-<username1>-<timestamp1>-<username2>-<timestamp2>. They can be even longer if all comments are written using non-Latin characters.
One of the drawbacks is that the [perma]link is copied using link encoding, for example “The field appears: %D8%A7%D9%84%D9%85%D9%8A%D8%AF%D8%A7%D9%86” and this may make it difficult to deal with it as internal links. Unless the encoding is replaced via online tools «URL Decoder».