There is a limit of 32000 inodes per directory on gallium filesystem. The Jenkins configuration changes are saved under /var/lib/jenkins/config-history/config and it is no more able to save.
From https://integration.wikimedia.org/ci/log/Warnings/
java.lang.RuntimeException: Could not create rootDir /var/lib/jenkins/config-history/config/2016-02-10_22-36-03
The dir has reached 32k inodes.