As seen in T285577: Several wikis have 0 articles for all ORES topics, we recently had an outage where articletopic queries returned zero results for numerous wikis. We were alerted to this by a community member, and it would have been better to have monitoring so we'd know there is a problem shortly after the code reached group2.
While GrowthExperiments shouldn't break as badly as it did when no topics are available (and we've fixed that), we do rely heavily on the articletopic query for our features.
This task exists for Growth-Team and Discovery-Search to talk about what kind of monitoring would be useful to implement.