The webservice error.log is filling with these errors:
2019-03-07 01:14:54: (chunk.c.553) opening temp-file failed: No such file or directory
Something about our temp files being cleaned up while still in use? It seems that the files in ~/app/var/cache/images/ are okay. I'm sure it's possible to make the error show us something more informative.
Analysis in T217815#5577987 points to tmpreaper removing the Grid Engine managed TMPDIR once empty of other files.